Apoptosis Reagents and Kits
ABclonal Technology Caspase-1 Rabbit pAb
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
Abcam Human SQSTM1 (p62) knockout HEK-293T cell lysate.
Human SQSTM1 (p62) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human MMP14 knockout A-431 cell lysate.
Human MMP14 knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PVR (Poliovirus Receptor) knockout A549 cell lysate.
Human PVR (Poliovirus Receptor) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human HLA-A knockout A-431 cell lysate.
Human HLA-A knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CHMP2B knockout A549 cell lysate.
Human CHMP2B knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human CD9 knockout A549 cell lysate.
Human CD9 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human NT5E knockout A-431 cell lysate.
Human NT5E knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human NEK9 knockout A-431 cell lysate.
Human NEK9 knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
CPC Scientific Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO 1MG
ONE-LETTER SEQUENCE: Ac-AAVALLPAVLLALLAPDEVD-CHOMOLECULAR FORMULA: C94H158N20O27MOLECULAR WEIGHT:2000.4STORAGE CONDITIONS: -20 5CRESEARCH AREA: ApoptosisREFERENCES: Y.Z. Lin et al., J. Biol. Chem., 271, 5305 (1996); D.W. Nicholson, Nature Biotechnol., 14, 297 (1996); M. Tewari et al., Cell, 81, 801 (1995)
CPC Scientific Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO 0.5MG
ONE-LETTER SEQUENCE: Ac-AAVALLPAVLLALLAPDEVD-CHOMOLECULAR FORMULA: C94H158N20O27MOLECULAR WEIGHT:2000.4STORAGE CONDITIONS: -20 5CRESEARCH AREA: ApoptosisREFERENCES: Y.Z. Lin et al., J. Biol. Chem., 271, 5305 (1996); D.W. Nicholson, Nature Biotechnol., 14, 297 (1996); M. Tewari et al., Cell, 81, 801 (1995)
ABclonal Technology FLCN Rabbit pAb
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Abcam Human IFNGR1 knockout HEK-293 cell lysate.
Human IFNGR1 knockout HEK-293 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement